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曹雪涛
N6-methyladenosine RNA modification–mediated cellular metabolism rewiring inhibits viral replication,Science,2019,Yang Liu, Yuling You , Zhike Lu, Jiang Yang , Panpan Li , Lun Liu , Henan Xu , Yamei Niu, Xuetao Cao,曹雪涛 A，43.644 [ PubMed ] -
刘德培
Diurnal oscillations of endogenous H2O2 sustained by p66Shc regulate circadian clocks. Nature Cell Biology .2019年, 21, 1553–1564. Jian-Fei P., et al. 刘德培, A, 20.551 [ PubMed ] -
彭小忠
Structure of heterophilic interaction between Nectin-like-4 and Nectin-like-1 molecules. Proc Natl Acad Sci U S A. 2019年, 116, 2068-2077. Xiao L., Tai A., et al. 彭小忠, A, 10.600 [ PubMed ] -
彭小忠
The antibiotic clofoctol suppresses glioma stem cell proliferation by activating KLF13. J Clin Invest. 2019年 ,29(8):3072-3085. Hu yan,.etal. 彭小忠, A, 12.282 [ PubMed ] -
彭小忠
Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Mammalian Neocortex, Developmental Cell. 2019年, 49, 764-785. Pengcheng S., Chao W., et al.彭小忠, A, 9.878 [ PubMed ] -
彭小忠
FHL3 links cell growth and self-renewal by modulating SOX4 in glioma. Cell Death Differ. 2019年, 26(5):796-811 Han W.,etal. 彭小忠, A, 8.086 [ PubMed ] -
彭小忠
The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signalling. Cell Reports. 2019年, 28 (3), 698-711. Li L.,etal. 彭小忠, A, 8.652 [ PubMed ] -
石磊
Zika virus NS3 is a canonical RNA helicase stimulated by NS5 RNA polymerase， Nucleic Acids Research.2019年. 石磊. A. 11.5 [ PubMed ] -
余佳
microRNA arm-imbalance partially from targets-mediated decay promotes gastric cancer progression. Nature Communications. 2019年, 10(1):4397. Zhang Z.,etal. 余佳, 11.878 [ PubMed ] -
张勇
Muscle-secreted granulocyte colony-stimulating factor functions as metabolic niche factor ameliorating loss of muscle stem cells in aged mice. EMBO Journal. 2019年, 38(24):e102154. Li H1, Chen Q.,etal. 张勇, 11.227 [ PubMed ] -
葛微
Quantitative proteomics reveals distinct composition of amyloid plaques in Alzheimer's disease. Alzheimers & Dementia,2019年,15(3): 429-440.Feng Xiong,.etal.葛微, A, 14.423 [ PubMed ] -
张建民
TSPO deficiency induces mitochondrial dysfunction, leading to hypoxia, angiogenesis and a growth-promoting metabolic shift towards glycolysis in glioblastoma. Neuro-Oncology. 2019年, Fu Y., etal. 张建民, A, 10.09 [ PubMed ] -
常永生
Dexamethasone-induced Kruppel-like factor 9 expression promotes hepatic gluconeogenesis and hyperglycemia J Clin Invest. 2019年, 129(6):2266-2278. Cui A, Fan H, Zhang Y,.etal. 常永生课题组, A, 12.282 [ PubMed ] -
黄波
Visualization of perforin/gasdermin/complement in real cell membranes using atomic force microscopy . Cellular & Molecular Immunology. 2019年, 16:611-620 Liu Y., etal. 黄波, A, 8.213 [ PubMed ] -
王晓月
Genome-Wide CRISPR-Cas9 Screen Reveals Selective Vulnerability of ATRX-Mutant Cancers to WEE1 Inhibition. cancer research. 2019年, Junbo L., et al. 王晓月, A, 8.378 [ PubMed ] -
zhanghongbing
mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis. Cell Death Differ. 2019年, 26(10):2015-2028. Li C., etal. 张宏冰, A, 8.309 [ PubMed ] -
曹雪涛
Nuclear hnRNPA2B1 initiates and amplifies the innate immune response to DNA viruses. Science，2019年 , 365, 6454, eaav0758 ,Lei Wang, Mingyue Wen, Xuetao Cao 曹雪涛 B2 43.644 [ PubMed ] -
余佳
Combined Single-Cell Profiling of lncRNAs and Functional Screening Reveals that H19 Is Pivotal for Embryonic Hematopoietic Stem Cell Development. Cell Stem Cell. 2019年, 24 (2), 285-298. Xu J., et al. 余佳, B1, 22.56 [ PubMed ] -
黄波
The softness of tumour-cell-derived microparticles regulates their drug-delivery efficiency. Nature Biomedical Engineering. 2019年, 3(9):729-740. Qingle Liang,etal. 黄波. B2 17.135 [ PubMed ]
重大疾病共性机制研究全国重点实验室
中国医学科学院基础医学研究所
北京协和医学院基础学院
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